Monday, April 8, 2013

Alzheimer's Disease

Introduction to Alzheimers

                 Alzheimers disorder is a progressive degenerative disease of

the brain. It is offset described by the German neuropathologist Alois

Alzheimer (1864-1915) in 1905. This disease worsens with forward age,

although there is no evidence that it is cause by the age process.

        The average life expectancy of a person with the disease is between

five and ten years, but some patients today can alive up to 15 years due to

improvements in do by and medical treatments. The cause of Alzheimers

has not been discovered yet and it cannot be possible to confirm a person

has Alzheimers until their autopsy following death.

How does Alzheimers develop

        What causes Alzheimers? strong no one know exactly the

development

of this debilitating disease. further recent advances has produced several clues

as to how it is born. Initially when we study the brain of a Alzheimers

victim, we focus on two specific beas. One is the cortex of the frontal and

cerebral lobes1. The second is the hippocampus (meaning seahorses in

Greek which it resembles2) which is located below the cerebral cortex and

responsible for short-term memory. If we study samples of these two

section, we would find three irregularities which are not found in normal

brain matter. These three are called neurofibrillary involves, neuritic plagues

and granulovacuolar degeneration3.

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        A nerve cell has numerous axons and dendrites coming out of it. A

neurofibrillary tangle is when the neuron changes. A number of dendrites

are missing and the nucleus is fill with protein filaments resembling steel

wool4.

Although all elderly people has a few of these coil shaped bundles in their

brain for they are normal indicators of aging, Alzheimers patients has more

than usual. Their presence commonly in the frontal and temporal lobes is a

indication of AD.

        Senile neuritic plagues...

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